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Rabbit Anti-GLIPR2/Cy7 Conjugated antibody (bs-8411R-Cy7)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-8411R-Cy7
英文名稱 Rabbit Anti-GLIPR2/Cy7 Conjugated antibody
中文名稱 Cy7標記的腦膠質瘤發(fā)病相關蛋白2抗體
別    名 GAPR 1; GAPR-1; GAPR1_HUMAN; GLI pathogenesis related 2; Glioma pathogenesis related protein 2; Glioma pathogenesis-related protein 2; GliPR 2; GLIPR2; Golgi associated plant pathogenesis related protein 1; Golgi associated PR 1 protein; Golgi-associated plant pathogenesis-related protein 1; Golgi-associated PR-1 protein; OTTMUSP00000007558; RP11-421H8.5; RP23-209M8.2; C77180; 5730414A08Rik; C9orf19.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  免疫學  神經生物學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 17kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GLIPR2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins that may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. GAPR-1 (Golgi-associated plant pathogenesis-related protein 1), also known as GLIPR2, is a 154 amino acid lipid anchor protein belonging to the CRISP family. GAPR-1 also shares similarity with the pathogenesis-related protein (PR) superfamily, and may play an important role in the immune system. Existing as a homodimer, GAPR-1 is highly expressed in lung and peripheral leukocytes with minor expression in liver and kidney. Containing a conserved sperm-coating protein (SCP) domain, GAPR-1 binds to negatively charged lipids and may be involved in the differentiation of epithelial cells into mesenchymal cells. Increased expression of GAPR-1 in kidney may contribute to the development of fibrosis.

Subunit:
Homodimer. Interacts with CAV1.

Subcellular Location:
Golgi apparatus membrane. Binds lipid-enriched microdomains of Golgi membranes not only by ionic interactions but also through the myristate.

Tissue Specificity:
Highest expression in lung and peripheral leukocytes, and minor expression in liver and kidney.

Similarity:
Belongs to the CRISP family.

Database links:
UniProtKB/Swiss-Prot: Q9H4G4.3

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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