產(chǎn)品編號 | bs-3801R-Gold |
英文名稱 | Rabbit Anti-Lambda Light Chain/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的λ輕鏈抗體 |
別 名 | Ig lambda chain C regions; Bence Jones protein; BJP; Constant region of lambda light chains; IGLC 1; IGLC 2; IGLC 3; IGLC; IGLC1; IGLC2; IGLC3; LAC1_HUMAN; Immunoglobulin lambda constant 1; Mcg marker; Paraprotein; Ig lambda-1 chain C regions. |
規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
說 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 22.5kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Lambda Light Chain |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. Subcellular Location: Cytoplasmic Similarity: Contains 1 Ig-like (immunoglobulin-like) domain. Database links: Entrez Gene: 3535 Human Entrez Gene: 3546 Human Entrez Gene: 8217 Human Omim: 147220 Human SwissProt: P01701 Human SwissProt: P01842 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 該抗體特異識別免疫球蛋白λ輕鏈,可用于鑒定白血病、漿細(xì)胞瘤以及某些非霍奇金氏淋巴瘤。這些腫瘤的共同特征是只限于單個輕鏈的表達(dá),因此輕鏈Kappa和Lamda可用于良惡性淋巴病變(反應(yīng)性淋巴細(xì)胞增生和淋巴瘤)的輔助性診斷。 |