| 產(chǎn)品編號 | bs-1916R-Gold |
| 英文名稱 | Rabbit Anti-RARRES1/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的視黃酸受體應(yīng)答蛋白1抗體 |
| 別 名 | Retinoic acid receptor responder protein 1; RAR-responsive protein TIG1; Tazarotene-induced gene 1 protein; TIG1_HUMAN. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 腫瘤 免疫學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Pig, Rabbit, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 33kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RARRES1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: RARRES1 (Retinoic acid receptor responder 1) is a retinoid-regulated gene whose expression is down-regulated through DNA hypermethylation. It was originally identified as a target gene that was induced by the synthetic retinoid tazarotene (AGN 190168). Its expression is upregulated by retinoic acid receptor-specific, but not by retinoid X receptor-specific retinoids. Although the function of RARRES1 is not entirely clear, it is thought to act as a tumor suppressor of a variety of human cancers since inactivation of RARRES1 is involved in the malignant progression of prostate cancer. It may also function as a cell adhesion molecule. Additionally, RARRES1 may also have protease inhibitor activity and inhibit the degradation of extracellular matrix. Subcellular Location: Membrane; Single-pass type II membrane protein (Potential). Similarity: Belongs to the protease inhibitor I47 (latexin) family. Database links: Entrez Gene: 5918 Human Omim: 605090 Human SwissProt: P49788 Human Unigene: 131269 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
