| 產(chǎn)品編號 | bs-4684R-PE-Cy5 |
| 英文名稱 | Rabbit Anti-Mammaglobin A/PE-Cy5 Conjugated antibody |
| 中文名稱 | PE-Cy5標(biāo)記的乳腺珠蛋白1抗體 |
| 別 名 | Mammaglobin 1; Mammaglobin A; Mammaglobin-1; Mammaglobin-A; MGB 1; MGB1; Prostatein C3 subunit; prostatein peptide C3; Prostatic steroid binding protein, allele C3(1); SCGB2A2; Secretoglobin; Secretoglobin Family 2A Member 2; SG2A2; UGB 2; UGB2; Uteroglobin; Psbpc3. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 細(xì)胞類型標(biāo)志物 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Mouse, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 8.4kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse Mammaglobin A |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement. Tissue Specificity: Mammary gland specific. Over-expressed in breast cancer. Similarity: Belongs to the secretoglobin family. Lipophilin subfamily. Database links: Entrez Gene: 4250 Human Entrez Gene: 100040203 Mouse Omim: 605562 Human SwissProt: Q13296 Human Unigene: 46452 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 乳腺球蛋白是一個乳腺相關(guān)糖蛋白，它是一個分泌素家族（包括子宮球蛋白和lipophilin）成員的遠(yuǎn)親。與其他分泌素家族成員不同，乳腺球蛋白的mRNA在乳腺組織中特異表達(dá)。在石蠟組織切片的檢測中，該抗體檢測乳腺癌組織中的乳腺珠蛋白敏感度高達(dá)80%。當(dāng)和其他乳腺特異標(biāo)記如GCDFP-15聯(lián)合應(yīng)用時，檢測乳腺珠蛋白敏感度高達(dá)84%。有資料表明檢測乳腺球蛋白，在鑒定原發(fā)癌是否發(fā)生轉(zhuǎn)移中起到至關(guān)重要的作用。 |
