| 產(chǎn)品編號 | bs-6081R-APC |
| 英文名稱 | Rabbit Anti-PDGFRL/APC Conjugated antibody |
| 中文名稱 | APC標(biāo)記的血小板源性生長因子受體β樣蛋白抗體 |
| 別 名 | PDGF receptor beta like tumor suppressor; PGFRL_HUMAN; PDGFR-like protein; PDGRL; PRLTS. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 免疫學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Horse, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 40kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PDGFRL |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: This protein is expressed in colon, lung and liver. Defects in PDGFRL are associated with colorectal cancer. Subunit: Forms a complex composed of PDGFRL, TNK2 and GRB2. Subcellular Location: Secreted (Probable). Tissue Specificity: Expressed in colon, lung and liver. DISEASE: Colorectal cancer (CRC) [MIM:114500]: A complex disease characterized by malignant lesions arising from the inner wall of the large intestine (the colon) and the rectum. Genetic alterations are often associated with progression from premalignant lesion (adenoma) to invasive adenocarcinoma. Risk factors for cancer of the colon and rectum include colon polyps, long-standing ulcerative colitis, and genetic family history. Note=The gene represented in this entry is involved in disease pathogenesis. Note=A polymorphism in PDGFRL has been reported to be associated with susceptibility to Behcet disease (PubMed:19815557). Behcet disease is a complex multiple-system disorder characterized by recurrent oral ulcerations, recurrent genital ulcerations, typical skin lesions, and uveitis. Behcet disease also involves joints, blood vessels, musculoskeletal, neurological systems, and the gastrointestinal tract. Similarity: Contains 2 Ig-like C2-type (immunoglobulin-like) domains. Database links: Entrez Gene: 5157 Human Entrez Gene: 68797 Mouse GenBank: NP_006198.1 Human Omim: 604584 Human SwissProt: Q15198 Human SwissProt: Q2PFX1 Monkey SwissProt: Q6PE55 Mouse Unigene: 458573 Human Unigene: 284246 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
