產(chǎn)品編號(hào) | bs-6081R-Gold |
英文名稱 | Rabbit Anti-PDGFRL/Gold Conjugated antibody |
中文名稱 | 膠體金標(biāo)記的血小板源性生長(zhǎng)因子受體β樣蛋白抗體 |
別 名 | PDGF receptor beta like tumor suppressor; PGFRL_HUMAN; PDGFR-like protein; PDGRL; PRLTS. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說(shuō) 明 書 | 100ul(10nm 15nm 35nm) |
研究領(lǐng)域 | 腫瘤 免疫學(xué) |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Horse, ) |
產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 40kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 0.4mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PDGFRL |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
產(chǎn)品介紹 |
background: This protein is expressed in colon, lung and liver. Defects in PDGFRL are associated with colorectal cancer. Subunit: Forms a complex composed of PDGFRL, TNK2 and GRB2. Subcellular Location: Secreted (Probable). Tissue Specificity: Expressed in colon, lung and liver. DISEASE: Colorectal cancer (CRC) [MIM:114500]: A complex disease characterized by malignant lesions arising from the inner wall of the large intestine (the colon) and the rectum. Genetic alterations are often associated with progression from premalignant lesion (adenoma) to invasive adenocarcinoma. Risk factors for cancer of the colon and rectum include colon polyps, long-standing ulcerative colitis, and genetic family history. Note=The gene represented in this entry is involved in disease pathogenesis. Note=A polymorphism in PDGFRL has been reported to be associated with susceptibility to Behcet disease (PubMed:19815557). Behcet disease is a complex multiple-system disorder characterized by recurrent oral ulcerations, recurrent genital ulcerations, typical skin lesions, and uveitis. Behcet disease also involves joints, blood vessels, musculoskeletal, neurological systems, and the gastrointestinal tract. Similarity: Contains 2 Ig-like C2-type (immunoglobulin-like) domains. Database links: Entrez Gene: 5157 Human Entrez Gene: 68797 Mouse GenBank: NP_006198.1 Human Omim: 604584 Human SwissProt: Q15198 Human SwissProt: Q2PFX1 Monkey SwissProt: Q6PE55 Mouse Unigene: 458573 Human Unigene: 284246 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |