產(chǎn)品編號 | IHC0629H |
英文名稱 | Human TFRC Ready-To-Use IHC Kit |
中文名稱 | 人轉(zhuǎn)鐵蛋白受體(CD71)即用型免疫組化試劑盒 |
別 名 | CD71; IMD46; p90; T9; TFR; TFR1; TFRC; TR; TRFR |
適用樣品基質(zhì) | FFPE tissue |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Serum transferrin receptor (sTfR) is used as a means of detecting erythropoietin (EPO) misuse by athletes and as a diagnostic test for anemias resulting from a number of conditions including rheumatoid arthritis, pregnancy, irritable bowel syndrome and in HIV patients. SWISS: P02786 Gene ID: 7037 |
產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded Human placenta tissue slide using IHC0629H (Human TFRC Kit).
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