| 產(chǎn)品編號(hào) | IHC0602R |
| 英文名稱 | Rat PSMD14 Ready-To-Use IHC Kit |
| 中文名稱 | 大鼠蛋白酶調(diào)解因子14即用型免疫組化試劑盒 |
| 別 名 | 2610312C03Rik; 3200001M20Rik; AA986732; PAD1; POH1; PSMD14; rpm11; RPN11 |
| 適用樣品基質(zhì) | FFPE tissue |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
The 26S proteasome is responsible for most intracellular proteolysis in eukaryotes. POH1 (also known as Rpn11 in yeast) subunit of the 19S complex is responsible for substrate deubiquitination during proteasomal degradation. POH1 appears to be a Zn21-dependent protease, unlike all other known deubiquitinating enzymes (DUBs) that are cysteine proteases. POH1 was first identified as the human functional homolog of the S. pombe pad1 gene, which confers moderate resistance to chemotherapeutic drugs, and also to ultraviolet light when transiently overproduced in mammalian cells. Poh1-induced drug resistance is mediated through AP-1 transcription factors. SWISS: O00487 Gene ID: 10213 |
| 產(chǎn)品圖片 |
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Immunohistochemical analysis of paraffin embedded Rat colon tissue slide using IHC0602R (Rat PSMD14 Kit).
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