| 產(chǎn)品編號(hào) | IHC0407H |
| 英文名稱 | Human phospho-EGFR (Ser695) Ready-To-Use IHC Kit |
| 中文名稱 | 人磷酸化表皮生長(zhǎng)因子受體即用型免疫組化試劑盒 |
| 別 名 | 9030024J15Rik; AI552599; ERBB; ERBB1; Errp; NISBD2; wa-2; EGFR; Avian erythroblastic leukemia viral (v erb b) oncogene homolog; Avian erythroblastic leukemia viral (verbb) oncogene homolog; Cell growth inhibiting protein 40; Cell proliferation inducing protein 61; EGF R; Epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog); Epidermal growth factor receptor (erythroblastic leukemia viral (v erb b) oncogene homolog avian); Epidermal growth factor receptor; erbb 1; Erbb; Erbb1; HER1; mENA; Oncogene ERBB; PIG61; Receptor tyrosine protein kinase ErbB 1; Receptor tyrosine protein kinase ErbB1; Urogastrone; wa2; Wa5; EGFR_HUMAN |
| 克 隆 號(hào) | |
| 適用樣品基質(zhì) | FFPE tissue |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
EGFR, epidermal growth factor receptor, is a receptor tyrosine kinases that signals in response to various growth factors. Overexpression has been linked to numerous types of cancer and EGFR is the target of both biological and small molecular therapeutics. EGFR is encoded by the EGFR gene located on chromosome 7 in humans. EGFR belongs to the HER/ERbB family of proteins that includes three other receptor tyrosine kinases, ERbB2, ERbB3, ERbB4. EGFR is a transmembrane receptor and binding of its cognate ligands such as EGF (Epidermal Growth Factor) and TGF alpha (Transforming Growth Factor alpha) to the extracellular domain leads to EGFR dimerization followed by autophosphorylation of the tyrosine residues in the cytoplasmic domain. Overexpression is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma. SWISS: P00533 Gene ID: 1956 |
| 產(chǎn)品圖片 |
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Immunohistochemical analysis of paraffin embedded human placenta tissue slide using IHC0407H (Human phospho-EGFR (Ser695) IHC Kit).
Immunohistochemical analysis of paraffin embedded human lung squamous cell carcinoma tissue slide using IHC0407H (Human phospho-EGFR (Ser695) IHC Kit).
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