產(chǎn)品編號(hào) | IHC0375H |
英文名稱 | Human OLIG2 Ready-To-Use IHC Kit |
中文名稱 | 人少突膠質(zhì)細(xì)胞轉(zhuǎn)錄因子2即用型免疫組化試劑盒 |
別 名 | AI604895; BHLHB1; BHLHE19; Olg-2; OLIG2; OLIGO2; PRKCBP2; RACK17; RK17; bHLHe19; oligodendrocyte transcription factor 2 |
克 隆 號(hào) | |
適用樣品基質(zhì) | FFPE tissue |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. Tissue specificity: Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable. SWISS: Q13516 Gene ID: 10215 |
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