| 產(chǎn)品編號(hào) | IHC0338H |
| 英文名稱 | Human SCF Ready-To-Use IHC Kit |
| 中文名稱 | 人干細(xì)胞生長(zhǎng)因子即用型免疫組化試劑盒 |
| 別 名 | DCUA; DFNA69; FPH2; FPHH; KL-1; SCF; Stem Cell Factor; C kit ligand; Ckit ligand; DKFZp686F2250; KIT ligand; Kitl; KITLG; KL 1; KL1; Mast cell growth factor; MGF; SF; SHEP7; Steel factor; Stem cell factor precursor; SCF_HUMAN |
| 克 隆 號(hào) | |
| 適用樣品基質(zhì) | FFPE tissue |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
Stem cell factor (SCF) is the ligand of the c-Kit oncogene and is expressed by various structural and inflammatory cells in the airways. Binding of SCF by the c-Kit receptor leads to homodimerization of the receptor and the activation of signalling pathways such as PI-3, PLC-gamma, Jak/STAT, and MAP kinase pathways. SCF expression leads to the induction of mast cell survival and the expression and release of histamine, pro-inflammatory cytokines and chemokines. The inhibition of the SCF/c-Kit pathway leads to a decrease in histamine levels, mast cell and eosinophil infiltration, IL-4 production and airway hyperresponsiveness, suggesting this pathway may be a useful therapeutic target in inflammatory diseases such as asthma. At least two isoforms of SCF are known to exist. SWISS: P21583 Gene ID: 4254 |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded human brain tissue slide using IHC0338H (Human SCF Kit).
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Immunohistochemical analysis of paraffin embedded human colon tissue slide using IHC0338H (Human SCF Kit).
Immunohistochemical analysis of paraffin embedded human prostate tumor tissue slide using IHC0338H (Human SCF Kit).
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