| 產(chǎn)品編號(hào) | IHC0336M |
| 英文名稱 | Mouse APAF1 Ready-To-Use IHC Kit |
| 中文名稱 | 小鼠凋亡蛋白活性因子-1即用型免疫組化試劑盒 |
| 別 名 | 6230400I06Rik; APAF-1; Apaf1l; fog; mKIAA0413; APAF 1; APAF1; CED4; DKFZp781B1145; KIAA0413 |
| 克 隆 號(hào) | |
| 適用樣品基質(zhì) | FFPE tissue |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
APAF1 gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. SWISS: O14727 Gene ID: 317 |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded mouse heart tissue slide using IHC0336M (Mouse APAF1 Kit).
Immunohistochemical analysis of paraffin embedded mouse spleen tissue slide using IHC0336M (Mouse APAF1 Kit).
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