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Human APAF1 Ready-To-Use IHC Kit (IHC0336H)  
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產品編號 IHC0336H
英文名稱 Human APAF1 Ready-To-Use IHC Kit
中文名稱 人凋亡蛋白活性因子-1即用型免疫組化試劑盒
別    名 6230400I06Rik; APAF-1; Apaf1l; fog; mKIAA0413; APAF 1; APAF1; CED4; DKFZp781B1145; KIAA0413  
克 隆 號
適用樣品基質 FFPE tissue
保存條件 Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt.
產品介紹 APAF1 gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms.

SWISS:
O14727

Gene ID:
317

產品圖片
Immunohistochemical analysis of paraffin embedded human heart tissue slide using IHC0336H (Human APAF1 Kit).
Immunohistochemical analysis of paraffin embedded human spleen tissue slide using IHC0336H (Human APAF1 Kit).
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