| 產(chǎn)品編號(hào) | bsm-63142R |
| 英文名稱 | phospho-PTPN11 (Y542) Recombinant Rabbit mAb |
| 中文名稱 | 磷酸化蛋白酪氨酸磷酸酶2重組兔單抗 |
| 別 名 | BPTP3; CFC; MGC14433; NS1; PTN11; PTP-1D; PTP-2C; PTP2C; PTPN11; SH-PTP2; SH-PTP3; SHP-2; Shp2; SHPTP2. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號(hào) | 8G3 |
| 交叉反應(yīng) | Human,Mouse |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,ICC/IF=1:50-200,IP=1:20-50
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 68 kDa |
| 檢測分子量 | 68 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human SHP2 around the phosphorylation site of Y542: GHE-pY-TNI |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
SHP-2 a SH2-containing a ubiquitously expressed tyrosine-specific protein phosphatase. It participates in signaling events downstream of receptors for growth factors, cytokines, hormones, antigens and extracellular matrices in the control of cell growth, differentiation, migration, and death. SWISS: Q06124 Gene ID: 5781 激酶和磷酸酶（Kinases and Phosphatases） SHP2(SH-PTP2)參與多種細(xì)胞內(nèi)信號(hào)傳導(dǎo) 如MAP kinase、 PI3k等途徑，SHP2也是許多其他原癌基因信號(hào)通路的重要組成部分，在細(xì)胞的增殖及分化等過程扮演重要的角色. |
