| 產(chǎn)品編號(hào) | bs-49061R |
| 英文名稱 | ANO1/TMEM16A Rabbit pAb |
| 中文名稱 | 跨膜蛋白16A/鈣激活氯離子通道抗體 |
| 別 名 | ANO 1; ANO1_HUMAN; Anoctamin 1; Anoctamin 1 calcium activated chloride channel; Anoctamin-1; Anoctamin1; Discovered on gastrointestinal stromal tumors protein 1; DOG 1; DOG1; FLJ10261; Membrane protein; Oral cancer overexpressed 2; Oral cancer overexpressed protein 2; ORAOV 2; ORAOV2; TAOS 2; TAOS2; TMEM 16A; TMEM16A; Transmembrane protein 16A(eight membrane spanning domains); Transmembrane protein 16A; Tumor amplified and overexpressed sequence 2; Tumor-amplified and overexpressed sequence 2. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 114 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | Recombinant human ANO1/TMEM16A: 37-333/986 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
TMEM16A (Transmembrane protein 16A) is an eight-transmembrane protein homologous to C12orf3, C11orf25 and FLJ34272 gene products and is amplified in various cancers. It acts as a calcium-activated chloride channel and is required for normal tracheal development. Function: Acts as a calcium-activated chloride channel. Required for normal tracheal development (By similarity). Subcellular Location: Cell membrane; Multi-pass membrane protein. Cytoplasm. Tissue Specificity: Broadly expressed with higher levels in liver and skeletal muscle. Similarity: Belongs to the anoctamin family. SWISS: Q5XXA6 Gene ID: 55107 Database links: Entrez Gene: 55107 Human Entrez Gene: 101772 Mouse Omim: 610108 Human SwissProt: Q5XXA6 Human SwissProt: Q8BHY3 Mouse Unigene: 503074 Human Unigene: 26700 Mouse Unigene: 162509 Rat |
| 產(chǎn)品圖片 |
Sample:
Lane 1: HepG2 (Human) Cell Lysate at 30 ug
Lane 2: A673 (Human) Cell Lysate at 30 ug
Lane 3: U-2OS (Human) Cell Lysate at 30 ug
Lane 4: MKN45 (Human) Cell Lysate at 30 ug
Primary: Anti-ANO1/TMEM16A (bs-49061R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 114-120 kD
Observed band size: 120 kD
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