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KREMEN1 Rabbit pAb (bs-16812R)  
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產品編號 bs-16812R
英文名稱 KREMEN1 Rabbit pAb
中文名稱 KREMEN1蛋白抗體
別    名 AV002070; Dickkopf receptor; KREM1_HUMAN; KREMEN; Kremen protein 1; Kremen protein 1 precursor; Kremen1; Kringle coding gene marking the eye and the nose; Kringle containing protein marking the eye and the nose; Kringle containing transmembrane protein 1; Kringle containing transmembrane protein; Kringle domain containing transmembrane protein 1; Kringle domain-containing transmembrane protein 1; Kringle-containing protein marking the eye and the nose; KRM1; RP23 293J16.1.  
研究領域 細胞生物  信號轉導  細胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse (predicted: Human,Rat,Sheep,Cow)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 50 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KREMEN1: 101-200/473 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008]

Function:
Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling (By similarity). {ECO:0000250}.

Subcellular Location:
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.

Similarity:
Contains 1 CUB domain.

SWISS:
Q96MU8

Gene ID:
83999

Database links:

Entrez Gene: 83999 Human

Omim: 609898 Human

SwissProt: Q96MU8 Human

Unigene: 229335 Human



產品圖片
Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti-KREMEN1 (bs-16812R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 50 kD Observed band size: 50 kD
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