| 產(chǎn)品編號(hào) | bs-16800R |
| 英文名稱 | KNCN Rabbit pAb |
| 中文名稱 | KNCN蛋白抗體 |
| 別 名 | FLJ32011; Kino; Kinocilin; Kncn; KNCN_HUMAN; L5; RP11-49P4.2. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 神經(jīng)生物學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | (predicted: Human) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 13 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KNCN: 1-100/124 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Kinocilin is a 124 amino acid multi-pass membrane protein that may play a role in the stabilization of dense microtubular networks, and may also participate in vesicular trafficking. Existing as two alternatively spliced isoforms, the gene encoding Kinocilin maps to human chromosome 1p33 and mouse chromosome 4 D1. Chromosome 1 spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. A large number of disease-associated genes are present on chromosome 1, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. Function: May plays a role in stabilizing dense microtubular networks or in vesicular trafficking. Subcellular Location: Membrane. SWISS: A6PVL3 Gene ID: 148930 Database links: Entrez Gene: 148930 Human Omim: 611455 Human SwissProt: A6PVL3 Human Unigene: 350764 Human |
