| 產(chǎn)品編號(hào) | bs-16661R |
| 英文名稱 | INO80B Rabbit pAb |
| 中文名稱 | PAP1結(jié)合蛋白抗體 |
| 別 名 | 2510009I23Rik; hIes2; high mobility group AT hook 1 like 4; High mobility group AT-hook 1-like 4; HMG1YL4; Hmga1l4; IES2; IES2 homolog; IN80B_HUMAN; INO80 complex subunit B; INO80B; PAP(Pim 1 associated protein) associated protein 1; PAP(Pim1 associated protein) associated protein 1; PAP 1 associated protein 1; PAP 1 binding protein; PAP 1BP; PAP-1-associated protein 1; PAP1 associated protein 1; PAP1 binding protein; PAP1BP; PAPA 1; PAPA-1; Papa1; zinc finger HIT domain containing protein 4; Zinc finger HIT domain-containing protein 4; zinc finger HIT type 4; Znhit4. |
| 研究領(lǐng)域 | 細(xì)胞生物 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 39 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human INO80B: 1-100/356 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a subunit of an ATP-dependent chromatin remodeling complex, INO80, which plays a role in DNA and nucleosome-activated ATPase activity and ATP-dependent nucleosome sliding. Readthrough transcription of this gene into the neighboring downstream gene, which encodes WW domain-binding protein 1, generates a non-coding transcript. [provided by RefSeq, Feb 2011] Function: Induces growth and cell cycle arrests at the G1 phase of the cell cycle. Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Subunit: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the helicase ATP-binding and the helicase C-terminal domain of INO80. Interacts with RP9. {ECO:0000269|PubMed:15556297, ECO:0000269|PubMed:16230350, ECO:0000269|PubMed:18922472, ECO:0000269|PubMed:21303910}. Subcellular Location: Nucleus. Nucleus; nucleolus. Similarity: Contains 1 HIT-type zinc finger. SWISS: Q9C086 Gene ID: 83444 Database links: Entrez Gene: 83444 Human Entrez Gene: 70020 Mouse SwissProt: Q9C086 Human SwissProt: Q99PT3 Mouse Unigene: 410786 Human Unigene: 27814 Mouse |
