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GPCR GPR87 Rabbit pAb (bs-16267R)  
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產(chǎn)品編號 bs-16267R
英文名稱 GPCR GPR87 Rabbit pAb
中文名稱 G蛋白偶聯(lián)受體87抗體
別    名 FKSG 78; FKSG78; G protein coupled receptor 87; G protein coupled receptor 95; G-protein coupled receptor 87; G-protein coupled receptor 95; GPCR87; GPR 87; GPR 95; GPR87; GPR87_HUMAN; GPR95; hGPCR87; KPG 002; KPG_002; MGC131898; Orphan GPCR 87; Probable G protein coupled receptor 87,  
研究領(lǐng)域 腫瘤  信號轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) Human
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 41 kDa
檢測分子量
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPCR GPR87: 151-250/358 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a G protein-coupled receptor and is located in a cluster of G protein-couple receptor genes on chromosome 3. The encoded protein has been shown to be overexpressed in lung squamous cell carcinoma (PMID:18057535) and regulated by p53 (PMID:19602589). [provided by RefSeq, Nov 2011]

Function:
Receptor for lysophosphatidic acid (LPA). Necessary for p53/TP53-dependent survival in response to DNA damage.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Expressed in placenta and prostate. Weaker expression in thymus. Not expressed in thalamus, hippocampus, pons or cerebellum. Overexpressed in squamous cell carcinoma of the lung.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
Q9BY21

Gene ID:
53836

Database links:

Entrez Gene: 53836 Human

Entrez Gene: 84111 Mouse

Omim: 606379 Human

SwissProt: Q9BY21 Human

SwissProt: Q99MT7 Mouse

Unigene: 591292 Human

Unigene: 60267 Mouse



產(chǎn)品圖片
Sample: DU145(Human) Cell Lysate at 30 ug Primary: Anti-GPCR GPR87 (bs-16267R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 41 kD Observed band size: 46 kD
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