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CORO2A Rabbit pAb (bs-13996R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-13996R
英文名稱 CORO2A Rabbit pAb
中文名稱 肌動(dòng)蛋白結(jié)合蛋白2A抗體
別    名 CLIPINB; COR2A_HUMAN; CORO 2A; CORO2A; Coronin 2A; Coronin actin binding protein 2A; Coronin like protein B; Coronin-2A; DKFZp686G19226; IR10; OTTHUMP00000021767; OTTHUMP00000021768; WD protein IR10; WD repeat containing protein 2; WD repeat protein 2; WD repeat-containing protein 2; WDR2.  
研究領(lǐng)域 細(xì)胞生物  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
克 隆 號(hào)
交叉反應(yīng) (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 60 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CORO2A: 301-400/525 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]

Subunit:
Binds actin (By similarity). Component of the N-Cor repressor complex, at least composed of NCOR1, NCOR2, HDAC3, TBL1X, TBL1R, CORO2A and GPS2.

Similarity:
Belongs to the WD repeat coronin family.
Contains 5 WD repeats.

SWISS:
Q92828

Gene ID:
7464

Database links:

Entrez Gene: 7464 Human

Omim: 602159 Human

SwissProt: Q92828 Human

Unigene: 113094 Human



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