產(chǎn)品編號(hào) | bs-13996R |
英文名稱 | CORO2A Rabbit pAb |
中文名稱 | 肌動(dòng)蛋白結(jié)合蛋白2A抗體 |
別 名 | CLIPINB; COR2A_HUMAN; CORO 2A; CORO2A; Coronin 2A; Coronin actin binding protein 2A; Coronin like protein B; Coronin-2A; DKFZp686G19226; IR10; OTTHUMP00000021767; OTTHUMP00000021768; WD protein IR10; WD repeat containing protein 2; WD repeat protein 2; WD repeat-containing protein 2; WDR2. |
研究領(lǐng)域 | 細(xì)胞生物 表觀遺傳學(xué) |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
克 隆 號(hào) | |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 60 kDa |
檢測(cè)分子量 | |
細(xì)胞定位 | 細(xì)胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human CORO2A: 301-400/525 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008] Subunit: Binds actin (By similarity). Component of the N-Cor repressor complex, at least composed of NCOR1, NCOR2, HDAC3, TBL1X, TBL1R, CORO2A and GPS2. Similarity: Belongs to the WD repeat coronin family. Contains 5 WD repeats. SWISS: Q92828 Gene ID: 7464 Database links: Entrez Gene: 7464 Human Omim: 602159 Human SwissProt: Q92828 Human Unigene: 113094 Human |