產(chǎn)品編號 | bs-2970R |
英文名稱 | PHGDH Rabbit pAb |
中文名稱 | 磷酸甘油酸脫氫酶抗體 |
別 名 | 3-phosphoglycerate dehydrogenase; D-3-phosphoglycerate dehydrogenase; EC 1.1.1.95; PDG; PGAD; PGD; PGDH; PGDH3; SERA; NLS; NLS1; 3PGDH; 3-PGDH; 3 PGDH; PHGDHD; HEL-S-113; SERA_HUMAN; EC:1.1.1.95; EC:1.1.1.399; EC:1.1.1.37; Malate dehydrogenase; 2-oxoglutarate reductase. |
研究領(lǐng)域 | 腫瘤 細胞生物 神經(jīng)生物學 信號轉(zhuǎn)導 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
克 隆 號 | |
交叉反應 | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
產(chǎn)品應用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 56 kDa |
檢測分子量 | |
細胞定位 | 細胞漿 細胞外基質(zhì) 分泌型蛋白 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PHGDH: 101-200/533 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known. [provided by RefSeq, Aug 2011] Function: Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 1/3. Subunit: Homotetramer DISEASE: Defects in PHGDH are the cause of phosphoglycerate dehydrogenase deficiency (PHGDH deficiency) . It is characterized by congenital microcephaly, psychomotor retardation, and seizures. Similarity: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. SWISS: O43175 Gene ID: 26227 Database links:
Entrez Gene: 26227 Human |
1、抗體溶解方法 | |
2、抗體修復方式 | |
3、常用試劑的配制 | |
4、免疫組化操作步驟 | |
5、免疫組化問題解答 | |
6、Western Blotting 操作步驟 | |
7、Western Blotting 問題解答 | |
8、關(guān)于肽鏈的設(shè)計 | |
9、多肽的溶解與保存 | |
10、酶標抗體效價測定程序 | |