| 產(chǎn)品編號 | bs-4684R |
| 英文名稱 | Mammaglobin A Rabbit pAb |
| 中文名稱 | 乳腺珠蛋白1抗體 |
| 別 名 | Mammaglobin 1; Mammaglobin A; Mammaglobin-1; Mammaglobin-A; MGB 1; MGB1; Prostatein C3 subunit; prostatein peptide C3; Prostatic steroid binding protein, allele C3(1); SCGB2A2; Secretoglobin; Secretoglobin Family 2A Member 2; SG2A2; UGB 2; UGB2; Uteroglobin; Psbpc3. 乳房珠蛋白1 |
 |
Specific References (1) | bs-4684R has been referenced in 1 publications.
[IF=3.743] Ying Liu. et al. 1H-NMR based metabolic study of MMTV-PyMT mice along with pathological progress to screen biomarkers for early diagnosis of breast cancer. Mol Omics. 2021 Dec;: IHC ; Mouse.
|
| 研究領域 | 腫瘤 細胞生物 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應 | (predicted: Rat) |
| 產(chǎn)品應用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 8.4 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞外基質(zhì) 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse Mammaglobin A: 41-96/96 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement. Tissue Specificity: Mammary gland specific. Over-expressed in breast cancer. Similarity: Belongs to the secretoglobin family. Lipophilin subfamily. Database links: Entrez Gene: 4250 Human Entrez Gene: 100040203 Mouse Omim: 605562 Human SwissProt: Q13296 Human Unigene: 46452 Human 乳腺球蛋白是一個乳腺相關糖蛋白，它是一個分泌素家族（包括子宮球蛋白和lipophilin）成員的遠親。與其他分泌素家族成員不同，乳腺球蛋白的mRNA在乳腺組織中特異表達。在石蠟組織切片的檢測中，該抗體檢測乳腺癌組織中的乳腺珠蛋白敏感度高達80%。當和其他乳腺特異標記如GCDFP-15聯(lián)合應用時，檢測乳腺珠蛋白敏感度高達84%。有資料表明檢測乳腺球蛋白，在鑒定原發(fā)癌是否發(fā)生轉移中起到至關重要的作用。 |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
