| 產(chǎn)品編號(hào) | bs-5788R |
| 英文名稱 | MMP20 Rabbit pAb |
| 中文名稱 | 基質(zhì)金屬蛋白酶20 |
| 別 名 | AI2A2; Enamel metalloproteinase; Enamelysin; Matrix metalloproteinase 20; Matrix metalloproteinase-20; MMP 20; MMP-20; MMP20; MMP20_HUMAN. |
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Specific References (2) | bs-5788R has been referenced in 2 publications.
[IF=2.816] Ogbureke et al. Matrix Metalloproteinase 20 Co-expression With Dentin Sialophosphoprotein in Human and Monkey Kidneys. (2016) J.Histochem.Cytochem. 64:623-36 IHC-P ; Human,Monkey.
[IF=2.42] Koli, Komal, Geetu Saxena, and Kalu UE Ogbureke. "Expression of Matrix Metalloproteinase (MMP)-20 and Potential Interaction with Dentin Sialophosphoprotein (DSPP) in Human Major Salivary Glands." Journal of Histochemistry & Cytochemistry (2015): 0022155415580817. WB, IHC-P, IF ; Human.
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| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 43 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞外基質(zhì) 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MMP20: 51-150/483 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation. Function: Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation. Subcellular Location: Secreted, extracellular space, extracellular matrix Tissue Specificity: Expressed specifically in the enamel organ. Post-translational modifications: Autoactivates at least at the 107-Asn-|-Tyr-108 site DISEASE: Defects in MMP20 are the cause of amelogenesis imperfecta hypomaturation type 2A2 (AI2A2) [MIM:612529]. AI2A2 is an autosomal recessive defect of enamel formation. The disorder involves both primary and secondary dentitions. The teeth have a shiny agar jelly appearance and the enamel is softer than normal. Brown pigment is present in middle layers of enamel. Similarity: Belongs to the peptidase M10A family. Contains 4 hemopexin-like domains. SWISS: O60882 Gene ID: 9313 Database links: Entrez Gene: 9313 Human Entrez Gene: 30800 Mouse Omim: 604629 Human SwissProt: O60882 Human SwissProt: P57748 Mouse Unigene: 591946 Human Unigene: 390121 Mouse Unigene: 218697 Rat |
