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TNFSF9 Rabbit pAb (bs-3851R)  
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產品編號 bs-3851R
英文名稱 TNFSF9 Rabbit pAb
中文名稱 腫瘤壞死因子配體超家族成員9抗體
別    名 Tumor necrosis factor ligand superfamily member 9; CD137L; TNLG5A; 4 1BB L; 4-1BB-L; 4 1BB ligand; 4 1BBL; CD137 ligand; homolog of mouse 4 1BB L; homolog of mouse 4 1BBL; ILA ligand(TNF related); Ly63l; receptor 4 1BB ligand; Tumor necrosis factor(ligand  
研究領域 腫瘤  細胞生物  免疫學  神經生物學  細胞表面分子  t-淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,Mouse,Rat
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 25-27 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TNFSF9: 101-200/254 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This cytokine belongs to the tumour necrosis factor (TNF) ligand family. It is a ligand for TNFRSF9, which is a costimulatory molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process, and in the generation of cytotoxic T cells. This cytokine is also shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is found to be expressed in various carcinoma cell lines, and is thought to be involved in T cell-tumour cell interaction.

Function:
Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.

Subunit:
Homotrimer.

Subcellular Location:
Membrane; Single-pass type II membrane protein.

Tissue Specificity:
Expressed in brain, placenta, lung, skeletal muscle and kidney.

Similarity:
Belongs to the tumor necrosis factor family.

SWISS:
P41273

Gene ID:
8744

Database links:

Entrez Gene: 8744 Human

Omim: 606182 Human

SwissProt: P41273 Human

Unigene: 1524 Human



產品圖片
Sample: Cerebrum (Rat) Lysate at 40 ug Primary: Anti-CD137L(bs-3851R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 25-27 kD Observed band size: 27 kD
Independently Validated Antibody, image provided by Science Direct, badge number 029578:Formalin-fixed and paraffin embedded human liver labeled with Anti-TNFSF9/CD137L Polyclonal Antibody, Unconjugated (bs-3851R) at 1:200 followed by conjugation to the secondary antibody and DAB staining
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