| 產(chǎn)品編號 | bs-4041R |
| 英文名稱 | Transaldolase 1 Rabbit pAb |
| 中文名稱 | 轉(zhuǎn)醛醇酶/EPS8L2抗體 |
| 別 名 | Dihydroxyacetone transferase; EPS8L2; Glycerone transferase; TAL; TAL H; TALDO; TALDO1; TALDOR; TALH; Transaldolase 1; Transaldolase1; Transaldolase-1; EC 2.2.1.2; TALDO_HUMAN. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 神經(jīng)生物學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 37 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Transaldolase 1: 145-250/337 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. Function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. Subunit: Homodimer. DISEASE: Transaldolase 1 deficiency (TALDO1 deficiency) [MIM:606003]: Results in telangiectases of the skin, hepatosplenomegaly, and enlarged clitoris. Note=The disease is caused by mutations affecting the gene represented in this entry. SWISS: Q9H6S3 Gene ID: 64787 Database links: Entrez Gene: 64787 Human Entrez Gene: 98845 Mouse Omim: 614988 Human SwissProt: Q9H6S3 Human SwissProt: Q99K30 Mouse Unigene: 55016 Human Unigene: 27451 Mouse Transaldolase 1稱醛羧移轉(zhuǎn)酶 或轉(zhuǎn)二羥丙酮基酶，經(jīng)研究該蛋白與多發(fā)性硬化癥有關(guān)。 |
