| 產(chǎn)品編號 | bs-3801R |
| 英文名稱 | Lambda Light Chain Rabbit pAb |
| 中文名稱 | λ輕鏈抗體 |
| 別 名 | IGLC1_HUMAN; Immunoglobulin lambda constant 1; IGLC1; Ig lambda chain C region MGC; Ig lambda-1 chain C region; IGLC; 免疫球蛋白λ輕鏈 |
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Specific References (1) | bs-3801R has been referenced in 1 publications.
[IF=5.241] Dou, Aixia. et al. Reelin depletion alleviates multiple myeloma bone disease by promoting osteogenesis and inhibiting osteolysis. Cell Death Discov. 2021 Aug;7(1):1-10 IHC ; Mouse.
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| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 22.5 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Lambda Light Chain: 41-106/106 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
All five immunoglobulin classes share the same basic four polypeptide chain structure of two heavy-chains and two light chains. There are five heavy chain types, and two light-chain types (Kappa and Lambda) both having a molecular weight of 22.5kDa. Any heavy-chain type can associate with either light-chain type, but on any immunoglobulin molecule both light-chains are of the same type. Kappa and Lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. Subcellular Location: Cytoplasmic Similarity: Contains 1 Ig-like (immunoglobulin-like) domain. SWISS: P01701 Gene ID: 8217 Database links: 該抗體特異識別免疫球蛋白λ輕鏈，可用于鑒定白血病、漿細(xì)胞瘤以及某些非霍奇金氏淋巴瘤。這些腫瘤的共同特征是只限于單個輕鏈的表達，因此輕鏈Kappa和Lamda可用于良惡性淋巴病變（反應(yīng)性淋巴細(xì)胞增生和淋巴瘤）的輔助性診斷。 |
