| 產(chǎn)品編號 | bs-1952R |
| 英文名稱 | Cellubrevin Rabbit pAb |
| 中文名稱 | 囊泡相關(guān)膜蛋白3抗體 |
| 別 名 | Vesicle Associated Membrane Protein 3; VAMP-3; VAMP 3; VAMP3; CEB; Synaptobrevin 3; Synaptobrevin-3; MGC108618; Vamp3; D130027G05Rik; VAMP3_HUMAN; Vesicle-associated membrane protein 3. |
| 研究領(lǐng)域 | 腫瘤 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號 | |
| 交叉反應(yīng) | (predicted: Human) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 11 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human VAMP-3/Cellubrevin: 2-60/100 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation. [provided by RefSeq, Jul 2008]. Function: SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network. Subcellular Location: Membrane; Single-pass type IV membrane protein (Probable). Cell junction, synapse, synaptosome. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the synaptobrevin family. Contains 1 v-SNARE coiled-coil homology domain. SWISS: Q9BRV4 Gene ID: 9341 Database links: Entrez Gene: 9341 Human Entrez Gene: 22319 Mouse Omim: 603657 Human SwissProt: Q15836 Human SwissProt: Q6FGG2 Human SwissProt: Q9BRV4 Human SwissProt: P63024 Mouse Unigene: 66708 Human Unigene: 273930 Mouse Unigene: 162135 Rat Unigene: 219999 Rat |
