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Thymidine kinase 1 Recombinant Rabbit mAb (bsm-52813R)  
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產(chǎn)品編號(hào) bsm-52813R
英文名稱 Thymidine kinase 1 Recombinant Rabbit mAb
中文名稱 胸苷激酶1重組兔單抗
別    名 cytosolic; KITH_HUMAN; Thymidine kinase 1; Thymidine kinase 1 soluble; Thymidine kinase 1 soluble isoform; Thymidine kinase; Thymidine kinase cytosolic; TK 1; TK 2; TK1; Tk1a; Tk1b; TK2.  
抗體來(lái)源 Rabbit
克隆類型 Recombinant
克 隆 號(hào) 9C1
交叉反應(yīng) Human
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:50-100,Flow-Cyt=1:20-100,ICC/IF=1:50-100,IP=1:20-50
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 25 kDa
檢測(cè)分子量
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 A synthesized peptide derived from human Thymidine kinase: 2-38 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Thymidine Kinase (TK1) is a highly conserved phosphotransferase that is present in most living cells. Thymidine Kinase catalyzes the phosphorylation reaction: deoxythymidine + ATP = deoxythymidine 5'-phosphate + ADP; it is thus involved in the reaction chain to introduce deoxythymidine into the DNA. Thymidine kinase is required for the action of many antiviral drugs, such as azidothymidine (AZT), and is is also used to select hybridoma cell lines in the production of monoclonal antibodies. Thymidine Kinase has many clinical applications as it is only present in anticipation of cell division. Because of this, Thymidine Kinase can be used as a proliferation marker in the diagnosis, treatment, and follow-up of malignant diseases, especially hematological malignancies. Thymidine Kinase may be observed as a monomer, dimer, trimer or tetramer.

SWISS:
P04183

Gene ID:
7083

產(chǎn)品圖片
Western blot analysis of Molt-4 cell lysate. Using Thymidine kinase 1 (bsm-52813R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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